25 citations · 49 across the 3 of their papers we have counts for
3 papers · 1 filter
In silico prediction of mutant HIV-1 proteases cleaving a target sequence
Jan H. Jensen, Martin Willemoës, Jakob R. Winther +1
HIV-1 protease represents an appealing system for directed enzyme re-design, since it has various different endogenous targets, a relatively simple structure and it is well studied…
BioFET-SIM Web Interface: Implementation and Two Applications
Martin R. Hediger, Jan H. Jensen, Luca De Vico
We present a web interface for the BioFET-SIM program. The web interface allows to conveniently setup calculations based on the BioFET-SIM multiple charges model. As an illustratio…
A Computational Methodology to Screen Activities of Enzyme Variants
Martin R. Hediger, Luca De Vico, Allan Svendsen +2
We present a fast computational method to efficiently screen enzyme activity. In the presented method, the effect of mutations on the barrier height of an enzyme-catalysed reaction…