DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase

Aysen L Erdem, Malgorzata Jaszczur, Jeffrey G Bertram +3

Escherichia coli DNA polymerase V (pol V), a heterotrimeric complex composed of UmuD'2C, is marginally active. ATP and RecA play essential roles in the activation of pol V for DNA…