activity
20092014
most citedSelscan: an efficient multi-threaded program to perform EHH-based scans for positive selection

903 citations · 941 across the 4 of their papers we have counts for

collaborators

5 papers

q-bio.PE2014

Comparing Evolutionary Rates Using An Exact Test for 2x2 Tables with Continuous Cell Entries

A. Morgan Thompson, M. Cyrus Maher, Lawrence H. Uricchio +2

Assessing the statistical significance of an observed 2x2 contingency table can easily be accomplished using Fisher's exact test (FET). However, if the cell entries are continuous…

q-bio.PE2014★ 903 cited

Selscan: an efficient multi-threaded program to perform EHH-based scans for positive selection

Zachary A Szpiech, Ryan D Hernandez

Haplotype-based scans to detect natural selection are useful to identify recent or ongoing positive selection in genomes. As both real and simulated genomic datasets grow larger, s…

q-bio.PE2013

A MOSAIC of methods: Improving ortholog detection through integration of algorithmic diversity

M. Cyrus Maher, Ryan D. Hernandez

Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, me…

q-bio.PE2013★ 38 cited

Robust forward simulations of recurrent hitchhiking

Lawrence H. Uricchio, Ryan D. Hernandez

Evolutionary forces shape patterns of genetic diversity within populations and contribute to phenotypic variation. In particular, recurrent positive selection has attracted signifi…

q-bio.PE2009

Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data

Ryan N. Gutenkunst, Ryan D. Hernandez, Scott H. Williamson +1

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an infer…