33 citations · 51 across the 2 of their papers we have counts for
2 papers
q-bio.GN2014★ 18 cited
VSEAMS: A pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes
Oliver S Burren, Hui Guo, Chris Wallace
Motivation: Genome-wide association studies (GWAS) have identified many loci implicated in disease susceptibility. Integration of GWAS summary statistics (p values) and functional…
q-bio.GN2012★ 33 cited
Methods for scoring the collective effect of SNPs: Minor alleles of common SNPs quantitatively affect traits/diseases and are under both positive and negative selection
Dejian Yuan, Zuobin Zhu, Xiaohua Tan +21
Most common SNPs are popularly assumed to be neutral. We here developed novel methods to examine in animal models and humans whether extreme amount of minor alleles (MAs) carried b…