355 citations · 529 across the 3 of their papers we have counts for
3 papers
A modified ziggurat algorithm for generating exponentially- and normally-distributed pseudorandom numbers
Christopher D McFarland
The Ziggurat Algorithm is a very fast rejection sampling method for generating PseudoRandom Numbers (PRNs) from common statistical distributions. The algorithm divides a distributi…
A tug-of-war between driver and passenger mutations in cancer and other adaptive processes
Christopher McFarland, Leonid Mirny, Kirill S. Korolev
Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few…
The impact of deleterious passenger mutations on cancer progression
Christopher D McFarland, Gregory V Kryukov, Shamil Sunyaev +1
Cancer progression is driven by a small number of genetic alterations accumulating in a neoplasm. These few driver alterations reside in a cancer genome alongside tens of thousands…