126 citations · 131 across the 3 of their papers we have counts for
4 papers
Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework
Gašper Tkačik, Julien O Dubuis, Mariela D Petkova +1
The concept of positional information is central to our understanding of how cells in a multicellular structure determine their developmental fates. Nevertheless, positional inform…
Morphogenesis at criticality?
Dmitry Krotov, Julien O. Dubuis, Thomas Gregor +1
Spatial patterns in the early fruit fly embryo emerge from a network of interactions among transcription factors, the gap genes, driven by maternal inputs. Such networks can exhibi…
Positional information, in bits
Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus +2
Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be…
Quantifying the Bicoid morphogen gradient in living fly embryos
Julien Dubuis, Alexander H Morrison, Martin Scheeler +1
In multicellular organisms, patterns of gene expression are established in response to gradients of signaling molecules. During fly development in early Drosophila embryos, the Bic…