4 papers
Complementing cell taxonomies with a multicellular functional analysis of tissues
Ricardo Omar Ramirez Flores, Philipp Sven Lars Schäfer, Leonie Küchenhoff +1
The application of single-cell molecular profiling coupled with spatial technologies has enabled charting cellular heterogeneity in reference tissues and in disease. This new wave…
Molecular causality in the advent of foundation models
Sebastian Lobentanzer, Pablo Rodriguez-Mier, Stefan Bauer +1
Correlation is not causation. As simple as this widely agreed-upon statement may seem, scientifically defining causality and using it to drive our modern biomedical research is imm…
Democratising Knowledge Representation with BioCypher
Sebastian Lobentanzer, Patrick Aloy, Jan Baumbach +26
Standardising the representation of biomedical knowledge among all researchers is an insurmountable task, hindering the effectiveness of many computational methods. To facilitate h…
Using Python to Dive into Signalling Data with CellNOpt and BioServices
Thomas Cokelaer, Julio Saez-Rodriguez
Systems biology is an inter-disciplinary field that studies systems of biological components at different scales, which may be molecules, cells or entire organism. In particular, s…