3 papers
math.OC2021
Design of a synthetic integral feedback circuit: dynamic analysis and DNA implementation
Corentin Briat, Christoph Zechner, Mustafa Khammash
The design and implementation of regulation motifs ensuring robust perfect adaptation are challenging problems in synthetic biology. Indeed, the design of high-yield robust metabol…
math.PR2014
Optimization-based Lyapunov function construction for continuous-time Markov chains with affine transition rates
Andreas Milias-Argeitis, Mustafa Khammash
We address the problem of Lyapunov function construction for a class of continuous-time Markov chains with affine transition rates, typically encountered in stochastic chemical kin…
math.PR2014
Unbiased estimation of second-order parameter sensitivities for stochastic reaction networks
Ankit Gupta, Mustafa Khammash
This paper deals with the problem of estimating second-order parameter sensitivities for stochastic reaction networks, where the reaction dynamics is modeled as a continuous time M…