197 citations · 463 across the 4 of their papers we have counts for
4 papers
Signaling Network Assessment of Mutations and Copy Number Variations Predicts Breast Cancer Subtype-specific Drug Targets
Naif Zaman, Lei Li, Maria Jaramillo +9
Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mecha…
Cancer systems biology in the genome sequencing era: Part 2, evolutionary dynamics of tumor clonal networks and drug resistance
Edwin Wang, Jinfeng Zou, Naif Zaman +3
A tumor often consists of multiple cell subpopulations (clones). Current chemo-treatments often target one clone of a tumor. Although the drug kills that clone, other clones overta…
Cancer systems biology in the genome sequencing era: Part 1, dissecting and modeling of tumor clones and their networks
Edwin Wang, Jinfeng Zou, Naif Zaman +3
Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation…
Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data
Edwin Wang, Naif Zaman, Shauna Mcgee +3
We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this…