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q-bio.GN2014
Sensitivity of mRNA Translation
Gilad Poker, Michael Margaliot, Tamir Tuller
Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, exit, and elong…
q-bio.GN2014
Maximizing Protein Translation Rate in the Nonhomogeneous Ribosome Flow Model: A Convex Optimization Approach
Gilad Poker, Yoram Zarai, Michael Margaliot +1
Translation is an important stage in gene expression. During this stage, macro-molecules called ribosomes travel along the mRNA strand linking amino-acids together in a specific or…