49 citations · 133 across the 4 of their papers we have counts for
5 papers
Modulation of DNA loop lifetimes by the free energy of loop formation
Yi-Ju Chen, Stephanie Johnson, Peter Mulligan +2
Storage and retrieval of the genetic information in cells is a dynamic process that requires the DNA to undergo dramatic structural rearrangements. DNA looping is a prominent examp…
Multiple Lac-mediated loops revealed by Bayesian statistics and tethered particle motion
Stephanie Johnson, Jan-Willem van de Meent, Rob Phillips +2
The bacterial transcription factor LacI loops DNA by binding to two separate locations on the DNA simultaneously. Despite being one of the best-studied model systems for transcript…
DNA sequence-dependent mechanics and protein-assisted bending in repressor-mediated loop formation
James Q. Boedicker, Hernan G. Garcia, Stephanie Johnson +1
As the chief informational molecule of life, DNA is subject to extensive physical manipulations. The energy required to deform double-helical DNA depends on sequence, and this mech…
Poly(dA:dT)-rich DNAs are highly flexible in the context of DNA looping
Stephanie Johnson, Yi-Ju Chen, Rob Phillips
Large-scale DNA deformation is ubiquitous in transcriptional regulation in prokaryotes and eukaryotes alike. Though much is known about how transcription factors and constellations…
Sequence Dependence of Transcription Factor-Mediated DNA Looping
Stephanie Johnson, Martin Lindén, Rob Phillips
DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: th…