55 citations · 72 across the 3 of their papers we have counts for
3 papers
The Allosteric Switching Mechanism in Bacteriophage MS2
Matthew R. Perkett, Dina T. Mirijanian, Michael F. Hagan
In this article we use all-atom simulations to elucidate the mechanisms underlying conformational switching and allostery within the coat protein of the bacteriophage MS2. Assembly…
Pathways for virus assembly around nucleic acids
Jason D Perlmutter, Matthew R Perkett, Michael F Hagan
Understanding the pathways by which viral capsid proteins assemble around their genomes could identify key intermediates as potential drug targets. In this work we use computer sim…
Using Markov State Models to Study Self-Assembly
Matthew R. Perkett, Michael F. Hagan
Markov state models (MSMs) have been demonstrated to be a powerful method for computationally studying intramolecular processes such as protein folding and macromolecular conformat…