65 citations · 65 across the 1 of their papers we have counts for
3 papers
The thermodynamics of computational copying in biochemical systems
Thomas E. Ouldridge, Christopher C. Govern, Pieter Rein ten Wolde
Living cells use readout molecules to record the state of receptor proteins, similar to measurements or copies in typical computational devices. But is this analogy rigorous? Can c…
How biochemical resources determine fundamental limits in cellular sensing
Christopher C. Govern, Pieter Rein ten Wolde
Living cells deploy many resources to sense their environments, including receptors, downstream signaling molecules, time and fuel. However, it is not known which resources fundame…
Fundamental Limits on Sensing Chemical Concentrations with Linear Biochemical Networks
Christopher C. Govern, Pieter Rein ten Wolde
Living cells often need to extract information from biochemical signals that are noisy. We study how accurately cells can measure chemical concentrations with signaling networks th…