activity
20132015
most citedUltrasmall Au10-12(SG)10-12 Nanomolecules for High Tumor Specificity and Cancer Radiotherapy

438 citations · 1.4k across the 5 of their papers we have counts for

collaborators

5 papers

physics.med-ph2015★ 246 cited

Ultrasmall Glutathione-Protected Gold Nanoclusters as Next Generation Radiotherapy Sensitizers with High Tumor Uptake and High Renal Clearance

Xiao-Dong Zhang, Zhentao Luo, Jie Chen +11

Radiotherapy is often the most straightforward first line cancer treatment for solid tumors. While it is highly effective against tumors, there is also collateral damage to healthy…

physics.bio-ph2014★ 71 cited

Storage of Gold Nanoclusters in Muscle Leads to their Biphasic in Vivo Clearance

Xiao-Dong Zhang, Zhentao Luo, Jie Chen +9

Ultrasmall gold nanoclusters show great potential in biomedical applications. Long term biodistribution, retention, toxicity, and pharmacokinetics profiles are prerequisites in the…

physics.bio-ph2014★ 438 cited

Ultrasmall Au10-12(SG)10-12 Nanomolecules for High Tumor Specificity and Cancer Radiotherapy

Xiao-Dong Zhang, Zhentao Luo, Jie Chen +7

Radiosensitizers can increase the local treatment efficacy under a relatively low and safe radiation dose, thereby facilitating tumor eradication and minimizing side effects. Here,…

physics.bio-ph2013★ 263 cited

Metabolizable Bi2Se3 Nanoplates: Biodistribution, Toxicity, and Uses for Cancer Radiation Therapy and Imaging

Xiao-Dong Zhang, Jie Chen, Yuho Min +12

Bi, a high atom number element, has a high photoelectric absorption coefficient, and Se element has anticancer activity. Hence, their compound chalcogenide (Bi2Se3) deserves a thor…

physics.bio-ph2013★ 378 cited

Enhanced Tumor Accumulation of Sub-2 nm Gold Nanoclusters for Cancer Radiation Therapy

Xiao-Dong Zhang, Jie Chen, Zhentao Luo +11

A new type of metabolizable and efficient radiosensitizer for cancer radiotherapy is presented in this study by combining ultrasmall Au nanoclusters (NCs, <2 nm) with biocompatible…