5 papers
Renal Blood Flow Quantification During Standard Myocardial Perfusion Imaging with Rubidium-82 Positron Emission Tomography
Hamid Abdollahi, Robert Doot, Raul Porto +6
Background: Renal blood flow (RBF) is an important marker of kidney health, but noninvasive assessment is not routinely used in clinical imaging. We evaluated the feasibility and p…
Beyond the Tumor: Recurrence-Prone Radiomics for Prognostication in Negative PSMA PET/CT scans of Prostate Cancer
Fereshteh Yousefirizi, Sara Harsini, Mobin Mohebi +14
In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and…
Virtual Theranostic Trials: New Approach Methodologies (NAMs) and Precision Radiopharmaceutical Therapies
Carlos F. Uribe, Hamid Abdollahi, Tahir Yusufaly +7
Radiopharmaceutical therapies are expanding rapidly, but clinical evidence generation is limited by operational constraints and biological heterogeneity in radiopharmaceutical deli…
Predictive Dosimetry in PSMA-Targeted Radiopharmaceutical Therapies: A PBPK Modeling and Machine Learning Study
Hamid Abdollahi, James Fowler, Carlos Uribe +1
Predictive dosimetry is central to enabling personalized radiopharmaceutical therapy (RPT), particularly in prostate specific membrane antigen (PSMA) targeted theranostics. In this…
Quantitative and Computational Radiobiology for Precision Radiopharmaceutical Therapies
Tahir Yusufaly, Hamid Abdollahi, Babak Saboury +1
This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the…