17 citations · 43 across the 5 of their papers we have counts for
6 papers
Statistical Evidence Measured on a Properly Calibrated Scale Across Nested and Non-nested Hypothesis Comparisons
V. J Vieland, S-C. Seok
Statistical modeling is often used to measure the strength of evidence for or against hypotheses on given data. We have previously proposed an information-dynamic framework in supp…
Host-to-host variation of ecological interactions in polymicrobial infections
Sayak Mukherjee, Kristin E. Weimer, Sang-Cheol Seok +5
Host-to-host variability with respect to interactions between microorganisms and multicellular hosts are commonly observed in infection and in homeostasis. However, the majority of…
In silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase Robustness
Sayak Mukherjee, Stephanie Rigaud, Sang-Cheol Seok +7
The inositol-phosphate messenger inositol(1,3,4,5)tetrakisphosphate (IP4) is essential for thymocyte positive selection by regulating plasma-membrane association of the protein tyr…
Cell responses only partially shape cell-to-cell variations in protein abundances in Escherichia coli chemotaxis
Sayak Mukherjee, Sang-Cheol Seok, Veronica J. Vieland +1
Cell-to-cell variations in protein abundance in clonal cell populations are ubiquitous in living systems. Since protein composition determines responses in individual cells, it sta…
Data-driven quantification of robustness and sensitivity of cell signaling networks
Sayak Mukherjee, Sang-Cheol Seok, Veronica J. Vieland +1
Robustness and sensitivity of responses generated by cell signaling networks has been associated with survival and evolvability of organisms. However, existing methods analyzing ro…
Measurement of statistical evidence on an absolute scale following thermodynamic principles
V. J. Vieland, J. Das, S. E. Hodge +1
Statistical analysis is used throughout biomedical research and elsewhere to assess strength of evidence. We have previously argued that typical outcome statistics (including p-val…