5 papers
BloClaw: An Omniscient, Multi-Modal Agentic Workspace for Next-Generation Scientific Discovery
Yao Qin, Yangyang Yan, Jinhua Pang +1
The integration of Large Language Models (LLMs) into life sciences has catalyzed the development of "AI Scientists." However, translating these theoretical capabilities into deploy…
TrinityDNA: A Bio-Inspired Foundational Model for Efficient Long-Sequence DNA Modeling
Qirong Yang, Yucheng Guo, Zicheng Liu +7
The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies…
MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging
Siyuan Li, Kai Yu, Anna Wang +7
Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit.…
EnTao-GPM: DNA Foundation Model for Predicting the Germline Pathogenic Mutations
Zekai Lin, Haoran Sun, Yucheng Guo +8
Distinguishing pathogenic mutations from benign polymorphisms remains a critical challenge in precision medicine. EnTao-GPM, developed by Fudan University and BioMap, addresses thi…
PFMBench: Protein Foundation Model Benchmark
Zhangyang Gao, Hao Wang, Cheng Tan +6
This study investigates the current landscape and future directions of protein foundation model research. While recent advancements have transformed protein science and engineering…