4 papers
Highly efficient intracellular chromobody delivery by mesoporous silica nanoparticles for antigen targeting and visualization in real time
Hsin-Yi Chiu, Wen Deng, Hanna Engelke +3
Chromobodies have recently drawn great attention as bioimaging nanotools. They offer antigen binding specificity and affinity comparable to conventional antibodies, but much smalle…
Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release
Stefan Datz, Christian Argyo, Michael Gattner +10
Effective and controlled drug delivery systems with on-demand release and targeting abilities have received enormous attention for biomedical applications. Here, we describe a nove…
Highly Efficient siRNA Delivery from Core-Shell Mesoporous Silica Nanoparticles with Multifunctional Polymer Caps
Karin Moeller, Katharina Mueller, Hanna Engelke +3
A new general route for siRNA delivery is presented combining porous core-shell silica nanocarriers with a modularly designed multifunctional block copolymer. Specifically, the int…
Lipid Bilayer-Coated Curcumin-based Mesoporous Organosilica Nanoparticles for Cellular Delivery
Stefan Datz, Hanna Engelke, Constantin v. Schirnding +2
Effective and controlled drug delivery systems with on-demand release abilities and biocompatible properties receive enormous attention for biomedical applications. Here, we descri…