47 citations · 47 across the 2 of their papers we have counts for
4 papers
Quantifying Reticulation in Phylogenetic Complexes Using Homology
Kevin Emmett, Raul Rabadan
Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular…
Multiscale Topology of Chromatin Folding
Kevin Emmett, Benjamin Schweinhart, Raul Rabadan
The three dimensional structure of DNA in the nucleus (chromatin) plays an important role in many cellular processes. Recent experimental advances have led to high-throughput metho…
Parametric Inference using Persistence Diagrams: A Case Study in Population Genetics
Kevin Emmett, Daniel Rosenbloom, Pablo Camara +1
Persistent homology computes topological invariants from point cloud data. Recent work has focused on developing statistical methods for data analysis in this framework. We show th…
Characterizing Scales of Genetic Recombination and Antibiotic Resistance in Pathogenic Bacteria Using Topological Data Analysis
Kevin J. Emmett, Raul Rabadan
Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire…