124 citations · 204 across the 2 of their papers we have counts for
2 papers
physics.bio-ph2015★ 80 cited
Shear-induced unfolding and enzymatic cleavage of full-length VWF multimers
Svenja Lippok, Matthias Radtke, Tobias Obser +5
Proteolysis of the multimeric blood coagulation protein von Willebrand Factor (VWF) by ADAMTS13 is crucial for prevention of microvascular thrombosis. ADAMTS13 cleaves VWF within t…
physics.bio-ph2009★ 124 cited
Shear-Induced Unfolding Activates von Willebrand Factor A2 Domain for Proteolysis
Carsten Baldauf, Reinhard Schneppenheim, Wolfram Stacklies +5
To avoid pathological platelet aggregation by von Willebrand factor (VWF), VWF multimers are regulated in size and reactivity for adhesion by ADAMTS13-mediated proteolysis in a she…