most citedRobust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression

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stat.AP2016★ 1k cited

Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression

Belinda Phipson, Stanley Lee, Ian J. Majewski +2

One of the most common analysis tasks in genomic research is to identify genes that are differentially expressed (DE) between experimental conditions. Empirical Bayes (EB) statisti…