11 citations · 19 across the 2 of their papers we have counts for
2 papers
q-bio.MN2016★ 8 cited
Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression
Iván M. Lengyel, Luis G. Morelli
Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production. Theoretical studie…
nlin.AO2014★ 11 cited
Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations
Iván M. Lengyel, Daniele Soroldoni, Andrew C. Oates +1
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence…