4 papers
Terbium-149 PET/CT: First Quantitative Imaging with a Clinical Long-Axial Field-of-View Scanner
Lorenzo Mercolli, Pascal V. Grundler, Anzhelika N. Moiseeva +4
Introduction: Terbium-149 (Tb) is a promising radionuclide for targeted therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low…
Beam Energy Measurement using a Bayesian Approach with the Stacked Foil Method
Alexander Gottstein, Lorenzo Mercolli, Eva Kasanda +7
We present a practical method to measure the energy of proton beams at a medical cyclotron using the stacked foil technique in combination with a Bayesian inference method. By meas…
First Positronium Lifetime Imaging with Scandium-44 on a Long Axial Field-of-view PET/CT
Lorenzo Mercolli, William M. Steinberger, Pascal V. Grundler +12
Purpose: 44Sc has been successfully produced, synthesized, labeled and first-in-human studies were conducted some years ago. The decay properties of 44Sc, together with being close…
Positronium Lifetime Imaging with the Biograph Vision Quadra using 124I
Lorenzo Mercolli, William M. Steinberger, Narendra Rathod +7
Purpose: Measuring the ortho-positronium (oPs) lifetime in human tissue bears the potential of adding clinically relevant information about the tissue microenvironment to conventio…