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q-bio.CB2016
A multiscale approach to the migration of cancer stem cells: mathematical modelling and simulations
Nikolaos Sfakianakis, Niklas Kolbe, Nadja Hellmann +1
We propose a multiscale model of the invasion of the extracellular matrix by two types of cancer cells, the differentiated cancer cells and the cancer stem cells. We assume that th…
q-bio.CB2015
A mathematical insight in the epithelial-mesenchymal-like transition in cancer cells and its effect in the invasion of the extracellular matrix
Nadja Hellmann, Niklas Kolbe, Nikolaos Sfakianakis
Current biological knowledge supports the existence of a secondary group of cancer cells within the body of the tumour that exhibits stem cell-like properties. These cells are term…