2 papers
cs.AI2016
Supervised Adverse Drug Reaction Signalling Framework Imitating Bradford Hill's Causality Considerations
Jenna Marie Reps, Jonathan M. Garibaldi, Uwe Aickelin +2
Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunat…
cs.AI2016
Refining adverse drug reaction signals by incorporating interaction variables identified using emergent pattern mining
Jenna M. Reps, Uwe Aickelin, Richard B. Hubbard
Purpose: To develop a framework for identifying and incorporating candidate confounding interaction terms into a regularised cox regression analysis to refine adverse drug reaction…