68 citations · 182 across the 6 of their papers we have counts for
6 papers
Protein Collapse is Encoded in the Folded State Architecture
Himadri S. Samanta, Pavel I. Zhuravlev, Michael Hinczewski +3
Natural protein sequences that self-assemble to form globular structures are compact with high packing densities in the folded states. It is known that proteins unfold upon additio…
Discrete step sizes of molecular motors lead to bimodal non-Gaussian velocity distributions under force
Huong T. Vu, Shaon Chakrabarti, Michael Hinczewski +1
Fluctuations in the physical properties of biological machines are inextricably linked to their functions. Distributions of run-lengths and velocities of processive molecular motor…
Phenomenological and microscopic theories for catch bonds
Shaon Chakrabarti, Michael Hinczewski, D. Thirumalai
Lifetimes of bound states of protein complexes or biomolecule folded states typically decrease when subject to mechanical force. However, a plethora of biological systems exhibit t…
Force-dependent switch in protein unfolding pathways and transition state movements
Pavel I. Zhuravlev, Michael Hinczewski, Shaon Chakrabarti +2
Although known that single domain proteins fold and unfold by parallel pathways, demonstration of this expectation has been difficult to establish in experiments. Unfolding rate, $…
Helicase processivity and not the unwinding velocity exhibits universal increase with force
David L. Pincus, Shaon Chakrabarti, D. Thirumalai
Helicases, involved in a number of cellular functions, are motors that translocate along singlestranded nucleic acid and couple the motion to unwinding double-strands of a duplex n…
Plasticity of hydrogen bond networks regulates mechanochemistry of cell adhesion complexes
Shaon Chakrabarti, Michael Hinczewski, D. Thirumalai
Mechanical forces acting on cell adhesion receptor proteins regulate a range of cellular functions by formation and rupture of non-covalent interactions with ligands. Typically, fo…