40 citations · 90 across the 5 of their papers we have counts for
7 papers
Understanding the role of transport velocity in biomotor-powered microtubule spool assembly
Amanda J. Tan, Dail E. Chapman, Linda S. Hirst +1
We examined the sensitivity of microtubule spools to transport velocity. Perhaps surprisingly, we determined that the steady-state number and size of spools remained constant over…
Tuning Multiple Motor Travel Via Single Motor Velocity
Jing Xu, Zhanyong Shu, Stephen J. King +1
Microtubule-based molecular motors often work in small groups to transport cargos in cells. A key question in understanding transport (and its regulation in vivo) is to identify th…
Interplay between velocity and travel distance of kinesin-based transport in the presence of tau
Jing Xu, Stephen J. King, Maryse Lapierre-Landry +1
Although the disease-relevant microtubule-associated protein tau is known to severely inhibit kinesin-based transport in vitro, the potential mechanisms for reversing this detrimen…
Microtubule Defects Influence Kinesin-Based Transport In Vitro
Winnie H. Liang, Qiaochu Li, K. M. Rifat Faysal +3
Microtubules are protein polymers that form "molecular highways" for long-range transport within living cells. Molecular motors actively step along microtubules to shuttle cellular…
Quantitative Determination of the Probability of Multiple-Motor Transport in Bead-Based Assays
Qiaochu Li, Stephen J. King, Ajay Gopinathan +1
With their longest dimension typically being less than 100 nm, molecular motors are significantly below the optical-resolution limit. Despite substantial advances in fluorescence-b…
Cooperative Protofilament Switching Emerges from Inter-Motor Interference in Multiple-Motor Transport
David Ando, Michelle K. Mattson, Jing Xu +1
Within living cells, the transport of cargo is accomplished by groups of molecular motors. Such collective transport could utilize mechanisms which emerge from inter-motor interact…