40 citations · 122 across the 7 of their papers we have counts for
8 papers
Understanding the role of transport velocity in biomotor-powered microtubule spool assembly
Amanda J. Tan, Dail E. Chapman, Linda S. Hirst +1
We examined the sensitivity of microtubule spools to transport velocity. Perhaps surprisingly, we determined that the steady-state number and size of spools remained constant over…
Tuning Multiple Motor Travel Via Single Motor Velocity
Jing Xu, Zhanyong Shu, Stephen J. King +1
Microtubule-based molecular motors often work in small groups to transport cargos in cells. A key question in understanding transport (and its regulation in vivo) is to identify th…
Interplay between velocity and travel distance of kinesin-based transport in the presence of tau
Jing Xu, Stephen J. King, Maryse Lapierre-Landry +1
Although the disease-relevant microtubule-associated protein tau is known to severely inhibit kinesin-based transport in vitro, the potential mechanisms for reversing this detrimen…
Microtubule Defects Influence Kinesin-Based Transport In Vitro
Winnie H. Liang, Qiaochu Li, K. M. Rifat Faysal +3
Microtubules are protein polymers that form "molecular highways" for long-range transport within living cells. Molecular motors actively step along microtubules to shuttle cellular…
Quantitative Determination of the Probability of Multiple-Motor Transport in Bead-Based Assays
Qiaochu Li, Stephen J. King, Ajay Gopinathan +1
With their longest dimension typically being less than 100 nm, molecular motors are significantly below the optical-resolution limit. Despite substantial advances in fluorescence-b…
Cooperative Protofilament Switching Emerges from Inter-Motor Interference in Multiple-Motor Transport
David Ando, Michelle K. Mattson, Jing Xu +1
Within living cells, the transport of cargo is accomplished by groups of molecular motors. Such collective transport could utilize mechanisms which emerge from inter-motor interact…
A Simple Experimental Model to Investigate Force Range for Membrane Nanotube Formation
Chai Lor, Joseph D. Lopes, Michelle K. Mattson-Hoss +2
The presence of membrane tubules in living cells is essential to many biological processes. In cells, one mechanism to form nanosized lipid tubules is via molecular motor induced b…
Time traces of individual kinesin motors suggest functional heterogeneity
Babu J. N. Reddy, Suvranta Tripathy, Jing Xu +5
Conventional analysis of in vitro assays of motor proteins rests on the assumption that all proteins with the same chemical composition function identically; however molecule-to-mo…