most citedUnfolding knots by proteasome-like systems: simulations of the behaviour of folded and neurotoxic proteins

36 citations · 36 across the 1 of their papers we have counts for

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1 paper

q-bio.BM2016★ 36 cited

Unfolding knots by proteasome-like systems: simulations of the behaviour of folded and neurotoxic proteins

Michał Wojciechowski, Àngel Gómez-Sicilia, Mariano Carrión-Vázquez +1

Knots in proteins have been proposed to resist proteasomal degradation. Ample evidence associates proteasomal degradation with neurodegeneration. One interesting possibility is tha…