15 citations · 30 across the 5 of their papers we have counts for
5 papers
Theory on the mechanisms of combinatorial binding of transcription factors with DNA
R. Murugan
We develop a theoretical framework on the mechanism of combinatorial binding of transcription factors (TFs) with their specific binding sites on DNA. We consider three possible mec…
Theory on the mechanism of site-specific DNA-protein interactions in the presence of traps
G. Niranjani, R. Murugan
The speed of site-specific binding of transcription factor (TFs) proteins with genomic DNA seems to be strongly retarded by the randomly occurring sequence traps. Traps are those D…
Theory on the mechanism of DNA renaturation: Stochastic nucleation and zipping
Gnanapragasam Niranjani, Rajamanickam Murugan
Renaturation of complementary single strands of DNA is one of the important processes that requires better understanding in the view of molecular biology and biological physics. He…
Theory on the mechanism of rapid binding of transcription factor proteins at specific-sites on DNA
Rajamanickam Murugan
We develop revised theoretical ideas on the mechanism by which the transcription factor proteins locate their specific binding sites on DNA faster than the three-dimensional (3D) d…
Theory on the Dynamics of Oscillatory Loops in the Transcription Factor Networks
Rajamanickam Murugan
We develop a detailed theoretical framework for various types of transcription factor gene oscillators. We further demonstrate that one can build genetic-oscillators which are tuna…