most citedNanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes

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physics.optics2016★ 1.3k cited

Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes

Francisco Balzarotti, Yvan Eilers, Klaus C. Gwosch +5

We introduce MINFLUX, a concept for localizing photon emitters in space. By probing the emitter with a local intensity minimum of excitation light, MINFLUX minimizes the fluorescen…