2 papers
physics.bio-ph2017
Mechanical interactions in bacterial colonies and the surfing probability of beneficial mutations
Fred F. Farrell, Matti Gralka, Oskar Hallatschek +1
Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures…
q-bio.PE2017
Convection shapes the trade-off between antibiotic efficacy and the selection for resistance in spatial gradients
Matti Gralka, Diana Fusco, Stephen Martis +1
Since penicillin was discovered about 90 years ago, we have become used to using drugs to eradicate unwanted pathogenic cells. However, using drugs to kill bacteria, viruses or can…