522 citations · 5.6k across the 44 of their papers we have counts for
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From fifty years ago, the birth of modern liquid-state science
David Chandler
The story told in this autobiographical perspective begins fifty years ago at the 1967 Gordon Research Conference on the Physics and Chemistry of Liquids. It traces developments in…
Pre-transition effects mediate forces of assembly between transmembrane proteins
Shachi Katira, Kranthi K. Mandadapu, Suriyanarayanan Vaikuntanathan +2
We present a mechanism for a generic and powerful force of assembly and mobility for transmembrane proteins in lipid bilayers. This force is a pre-transition (or pre-melting) effec…
The molecular structure of the interface between water and a hydrophobic substrate is liquid-vapor like
Adam P. Willard, David Chandler
With molecular simulation for water and a tunable hydrophobic substrate, we apply the instantaneous interface construction [A. P. Willard and D. Chandler, J. Phys. Chem. B, 114, 19…
Water Evaporation: A Transition Path Sampling Study
Patrick Varilly, David Chandler
We use transition path sampling to study evaporation in the SPC/E model of liquid water. Based on thousands of evaporation trajectories, we characterize the members of the transiti…
Sitting at the edge: How biomolecules use hydrophobicity to tune their interactions and function
Amish J. Patel, Patrick Varilly, Sumanth N. Jamadagni +3
Water near hydrophobic surfaces is like that at a liquid-vapor interface, where fluctuations in water density are substantially enhanced compared to that in bulk water. Here we use…
Quantifying density fluctuations in volumes of all shapes and sizes using indirect umbrella sampling
Amish J. Patel, Patrick Varilly, David Chandler +1
Water density fluctuations are an important statistical mechanical observable that is related to many-body correlations, as well as hydrophobic hydration and interactions. Local wa…
Extended surfaces modulate and can catalyze hydrophobic effects
Amish J. Patel, Patrick Varilly, Sumanth N. Jamadagni +3
Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affect hydrophobic phenomena, we use molecular simulations and theory to study h…
Lectures on Molecular- and Nano-scale Fluctuations in Water
David Chandler, Patrick Varilly
This manuscript is the written form of three lectures delivered by David Chandler at the International School of Physics "Enrico Fermi", Course CLXXVI - "Complex materials in physi…
An improved coarse-grained model of solvation and the hydrophobic effect
Patrick Varilly, Amish J. Patel, David Chandler
We present a coarse-grained lattice model of solvation thermodynamics and the hydrophobic effect that implements the ideas of Lum-Chandler-Weeks (LCW) theory [J. Phys. Chem. B 103,…
Instantaneous Liquid Interfaces
Adam P. Willard, David Chandler
We describe and illustrate a simple procedure for identifying a liquid interface from atomic coordinates. In particular, a coarse grained density field is constructed, and the inte…
Dynamics on the Way to Forming Glass: Bubbles in Space-time
David Chandler, Juan P. Garrahan
We review a theoretical perspective of the dynamics of glass forming liquids and the glass transition. It is a perspective we have developed with our collaborators during this deca…