96 citations · 241 across the 6 of their papers we have counts for
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physics.bio-ph2016★ 9 cited
Stochastic multi-scale models of competition within heterogeneous cellular populations: simulation methods and mean-field analysis
Roberto de la Cruz, Pilar Guerrero, Fabian Spill +1
We propose a modelling framework to analyse the stochastic behaviour of heterogeneous, multi-scale cellular populations. We illustrate our methodology with a particular example in…
q-bio.MN2016★ 96 cited
Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches
Ruben Perez-Carrasco, Pilar Guerrero, James Briscoe +1
During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guid…