2 papers
stat.ME2026
Efficient Response-Adaptive Randomization for Multi-arm Trials with Prioritized Composite Endpoints
Ayon Mukherjee
The efficient randomized-adaptive design attains the minimal possible variance of the allocation proportion for any pre-specified target and has been extended from two to several t…
stat.AP2025
Bayesian Optimal Phase II design with optimised stopping boundaries and response-adaptive randomisation
Connor Fitchett, Ayon Mukherjee, SofÃa S. Villar +1
The Bayesian Optimal Phase II (BOP2) framework is a flexible trial design that can naturally facilitate complex adaptations due to its Bayesian setting. BOP2 uses equal randomisati…