3 papers
stat.AP2018
Accurate and Efficient Estimation of Small P-values with the Cross-Entropy Method: Applications in Genomic Data Analysis
Yang Shi, Mengqiao Wang, Weiping Shi +3
Small -values are often required to be accurately estimated in large-scale genomic studies for the adjustment of multiple hypothesis tests and the ranking…
stat.ME2016
A Unified Model for Differential Expression Analysis of RNA-seq Data via L1-Penalized Linear Regression
Kefei Liu, Jieping Ye, Yang Yang +2
The RNA-sequencing (RNA-seq) is becoming increasingly popular for quantifying gene expression levels. Since the RNA-seq measurements are relative in nature, between-sample normaliz…
stat.CO2016
Efficiently estimating small p-values in permutation tests using importance sampling and cross-entropy method
Yang Shi, Huining Kang, Ji-Hyun Lee +1
Permutation tests are widely used for statistical hypothesis testing when the sampling distribution of the test statistic under the null hypothesis is analytically intractable or u…