3 papers
q-bio.CB2018
Immunological recognition by artificial neural networks
Jin Xu, Junghyo Jo
The binding affinity between the T-cell receptors (TCRs) and antigenic peptides mainly determines immunological recognition. It is not a trivial task that T cells identify the digi…
q-bio.CB2017
Broad cross-reactivity of the T-cell repertoire achieves specific and sufficiently rapid target searching
Jin Xu, Junghyo Jo
The molecular recognition of T-cell receptors is the hallmark of the adaptive immunity. Given the finiteness of the T-cell repertoire, individual T-cell receptors are necessary to…
q-bio.TO2016
A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations
Dong-Ho Park, Taegeun Song, Danh-Tai Hoang +2
Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic…