52 citations · 79 across the 5 of their papers we have counts for
6 papers
Reconstructing an epigenetic landscape using a genetic `pulling' approach
Michael Assaf, Shay Be'er, Elijah Roberts
Cells use genetic switches to shift between alternate stable gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Conceptually, these st…
Reducing the extinction risk of stochastic populations via non-demographic noise
Shay Be'er, Michael Assaf
We consider non-demographic noise in the form of uncertainty in the reaction step size, and reveal a dramatic effect this noise may have on the stability of self-regulating populat…
Rare events in stochastic populations under bursty reproduction
Shay Be'er, Michael Assaf
Recently, a first step was made by the authors towards a systematic investigation of the effect of reaction-step-size noise - uncertainty in the step size of the reaction - on the…
Effect of reaction step-size noise on the switching dynamics of stochastic populations
Shay Be'er, Metar Heller-Algazi, Michael Assaf
In genetic circuits, when the mRNA lifetime is short compared to the cell cycle, proteins are produced in geometrically-distributed bursts, which greatly affects the cellular switc…
The dynamics of simple gene-network motifs subject to extrinsic fluctuations
Elijah Roberts, Shay Be'er, Chris Bohrer +2
Cellular processes do not follow deterministic rules; even in identical environments genetically identical cells can make random choices leading to different phenotypes. This rando…
Colonization of a territory by a stochastic population under a strong Allee effect and a low immigration pressure
Shay Be'er, Michael Assaf, Baruch Meerson
We study the dynamics of colonization of a territory by a stochastic population at low immigration pressure. We assume a sufficiently strong Allee effect that introduces, in determ…