5 citations · 7 across the 2 of their papers we have counts for
3 papers
COMO: A Pipeline for Multi-Omics Data Integration in Metabolic Modeling and Drug Discovery
Brandt Bessell, Josh Loecker, Zhongyuan Zhao +5
Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without so…
Systems Perturbation Analysis of a Large Scale Signal Transduction Model Reveals Potentially Influential Candidates for Cancer Therapeutics
Bhanwar Lal Puniya, Laura Allen, Colleen Hochfelder +2
Dysregulation in signal transduction pathways can lead to a variety of complex disorders, including cancer. Computational approaches such as network analysis are important tools to…
SBML Qualitative Models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools
Claudine Chaouiya, Duncan Berenguier, Sarah M Keating +21
Background: Qualitative frameworks, especially those based on the logical discrete formalism, are increasingly used to model regulatory and signalling networks. A major advantage o…