Resolving Single-Peptide Phosphorylation Dynamics in Plasmonic Nanopores using Physics-Informed Bi-Path Model

Mulusew W. Yaltaye, Yingqi Zhao, Kuo Zhan +2

Protein phosphorylation provides a dynamic readout of cellular signaling yet remains difficult to detect at low abundance and stoichiometry. Single-molecule surface-enhanced Raman…