62 citations · 172 across the 6 of their papers we have counts for
6 papers
Free-Energy Transduction in Chemical Reaction Networks: from Enzymes to Metabolism
Artur Wachtel, Riccardo Rao, Massimiliano Esposito
We provide a rigorous definition of free-energy transduction and its efficiency in arbitrary -- linear or nonlinear -- open chemical reaction networks (CRNs) operating at steady st…
Thermodynamically Consistent Coarse Graining of Biocatalysts beyond Michaelis--Menten
Artur Wachtel, Riccardo Rao, Massimiliano Esposito
Starting from the detailed catalytic mechanism of a biocatalyst we provide a coarse-graining procedure which, by construction, is thermodynamically consistent. This procedure provi…
Dissipation in noisy chemical networks: The role of deficiency
Matteo Polettini, Artur Wachtel, Massimiliano Esposito
We study the effect of intrinsic noise on the thermodynamic balance of complex chemical networks subtending cellular metabolism and gene regulation. A topological network property…
Fluctuating Currents in Stochastic Thermodynamics II. Energy Conversion and Nonequilibrium Response in Kinesin Models
Bernhard Altaner, Artur Wachtel, Jürgen Vollmer
Unlike macroscopic engines, the molecular machinery of living cells is strongly affected by fluctuations. Stochastic Thermodynamics uses Markovian jump processes to model the rando…
Fluctuating Currents in Stochastic Thermodynamics I. Gauge Invariance of Asymptotic Statistics
Artur Wachtel, Jürgen Vollmer, Bernhard Altaner
Stochastic Thermodynamics uses Markovian jump processes to model random transitions between observable mesoscopic states. Physical currents are obtained from anti-symmetric jump ob…
Fluctuation Spectra and Coarse Graining in Stochastic Dynamics
Artur Wachtel
Fluctuations in small biological systems can be crucial for their function. Large-deviation theory characterizes such rare events from the perspective of stochastic processes. In m…