197 citations · 1.2k across the 18 of their papers we have counts for
18 papers
Wrapping pathways of anisotropic dumbbell particles by giant unilamellar vesicles
Ali Azadbakht, Billie Meadowcroft, Thijs Varkevisser +2
Endocytosis is a key cellular process involved in the uptake of nutrients, pathogens or the diagnosis and therapy of diseases. Most studies have focused on spherical objects, where…
Minimal coarse-grained models for molecular self-organisation in biology
Anne E. Hafner, Johannes Krausser, Anđela Šarić
The molecular machinery of life is largely created via self-organisation of individual molecules into functional assemblies. Minimal coarse-grained models, where a whole macromolec…
Reaction rate theory for supramolecular kinetics: application to protein aggregation
Thomas C. T. Michaels, Lucie X. Liu, Samo Curk +3
Probing the reaction mechanisms of supramolecular processes in soft- and biological matter, such as protein aggregation, is inherently challenging. These processes emerge from the…
Controlling cargo trafficking in multicomponent membranes
Tine Curk, Peter Wirnsberger, Jure Dobnikar +2
Biological membranes typically contain a large number of different components dispersed in small concentrations in the main membrane phase, including proteins, sugars, and lipids o…
Curvature variation controls particle aggregation on fluid vesicles
Afshin Vahid, Anđela Šarić, Timon Idema
Cellular membranes exhibit a large variety of shapes, strongly coupled to their function. Many biological processes involve dynamic reshaping of membranes, usually mediated by prot…
Numerical Evidence for Thermally Induced Monopoles
Peter Wirnsberger, Domagoj Fijan, Roger Adam Lightwood +3
Electrical charges are conserved. The same would be expected to hold for magnetic charges, yet magnetic monopoles have never been observed. It is therefore surprising that the laws…
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
Anđela Šarić, Thomas C. T. Michaels, Alessio Zaccone +2
Nucleation processes are at the heart of a large number of phenomena, from cloud formation to protein crystallization. A recently emerging area where nucleation is highly relevant…
Melting transition in lipid vesicles functionalised by mobile DNA linkers
S. J. Bachmann, J. Kotar, L. Parolini +4
We study phase behaviours of lipid--bilayer vesicles functionalised by ligand--receptor complexes made of synthetic DNA by introducing a modelling framework and a dedicated experim…
Lipid membrane-mediated attractions between curvature inducing objects
Casper van der Wel, Afshin Vahid, Anđela Šarić +3
The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical consi…
Non-equilibrium simulations of thermally induced electric fields in water
Peter Wirnsberger, Domagoj Fijan, Anđela Šarić +3
Using non-equilibrium molecular dynamics simulations, it has been recently demonstrated that water molecules align in response to an imposed temperature gradient, resulting in an e…
Crucial role of non-specific interactions in amyloid nucleation
Anđela Šarić, Yassmine C. Chebaro, Tuomas P. J. Knowles +1
Protein oligomers have been implicated as toxic agents in a wide range of amyloid-related diseases. Yet it has remained unsolved whether the oligomers are a necessary step in the f…
Living clusters and crystals from low density suspensions of active colloids
B. M. Mognetti, A. Šarić, S. Angioletti-Uberti +3
Recent studies aimed at investigating artificial analogs of bacterial colonies have shown that low-density suspensions of self-propelled particles confined in two dimensions can as…
Anomalous Thermomechanical Properties of a Self-propelled Colloidal Fluid
S. A. Mallory, A. Šarić, C. Valeriani +1
We use numerical simulations to compute the equation of state of a suspension of spherical, self-propelled nanoparticles. We study in detail the effect of excluded volume interacti…
Mechanism of membrane tube formation induced by adhesive nanocomponents
Andela Šarić, Angelo Cacciuto
We report numerical simulations of membrane tubulation driven by large colloidal particles. Using Monte Carlo simulations we study how the process depends on particle size, concent…
Fluid membranes can drive linear aggregation of adsorbed spherical nanoparticles
Andela Šarić, Angelo Cacciuto
Using computer simulations we show that lipid membranes can mediate linear aggregation of spherical nanoparticles binding to it for a wide range of biologically relevant bending ri…
Soft elastic surfaces as a platform for particle self-assembly
Andela Šarić, Angelo Cacciuto
We perform numerical simulations to study self-assembly of nanoparticles mediated by an elastic planar surface. We show how the nontrivial elastic response to deformations of these…
Packing of soft asymmetric dumbbells
Andela Šarić, Behnaz Bozorgui, Angelo Cacciuto
We use numerical simulations to study the phase behavior of a system of purely repulsive soft dumbbells as a function of size ratio of the two components and their relative degree…
Effective elasticity of a flexible filament bound to a deformable cylindrical surface
Andela Šarić, Josep C. Pàmies, Angelo Cacciuto
We use numerical simulations to show how a fully flexible filament binding to a deformable cylindrical surface may acquire a macroscopic persistence length and a helical conformati…