23 citations · 23 across the 2 of their papers we have counts for
2 papers
q-bio.PE2015
Evolutionary interplay between structure, energy and epistasis in the coat protein of the phage family
Rodrigo A. F. Redondo, Harold P. de Vladar, Tomasz Włodarski +1
Viral capsids are structurally constrained by interactions amongst the amino acids of the constituting proteins. Therefore, epistasis is expected to evolve amongst sites engaged in…
q-bio.PE2010★ 23 cited
The statistical mechanics of a polygenic characterunder stabilizing selection, mutation and drift
Harold P. de Vladar, Nick Barton
By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation, and genetic drift…