3 papers
physics.bio-ph2012
Ensemble-based characterization of unbound and bound states on protein energy landscape
Anatoly M. Ruvinsky, Tatsiana Kirys, Alexander V. Tuzikov +1
Characterization of protein energy landscape and conformational ensembles is important for understanding mechanisms of protein folding and function. We studied ensembles of bound a…
physics.bio-ph2011
Structure fluctuations and conformational changes in protein binding
Anatoly M. Ruvinsky, Tatsiana Kirys, Alexander V. Tuzikov +1
Structure fluctuations and conformational changes accompany all biological processes involving macromolecules. The paper presents a classification of protein residues based on the…
q-bio.BM2010
Side-chain conformational changes upon protein-protein association
Anatoly M. Ruvinsky, Tatsiana Kirys, Alexander V. Tuzikov +1
Conformational changes upon protein-protein association are the key element of the binding mechanism. The study presents a systematic large-scale analysis of such conformational ch…