Daniel Cresta

most citedTime to revisit the endpoint dilution assay and to replace TCID

_{50}

and PFU as measures of a virus sample's infection concentration

53 citations · 54 across the 2 of their papers we have counts for

collaborators

2 papers

q-bio.CB2022★ 1 cited

Stochastic failure of cell infection post viral entry: Implications for infection outcomes and antiviral therapy

Christian Quirouette, Daniel Cresta, Jizhou Li +3

A virus infection can be initiated with very few or even a single infectious virion, and as such can become extinct, i.e. stochastically fail to take hold or spread significantly.…

q-bio.QM2021★ 53 cited

Time to revisit the endpoint dilution assay and to replace TCID $_{50}$ and PFU as measures of a virus sample's infection concentration

Daniel Cresta, Donald C. Warren, Christian Quirouette +4

The infectivity of a virus sample is measured by the infections it causes, via a plaque or focus forming assay (PFU or FFU) or an endpoint dilution (ED) assay (TCID $_{50}$ , CCID$_{…

Stochastic failure of cell infection post viral entry: Implications for infection outcomes and antiviral therapy

Time to revisit the endpoint dilution assay and to replace TCID50​ and PFU as measures of a virus sample's infection concentration

Time to revisit the endpoint dilution assay and to replace TCID $_{50}$ and PFU as measures of a virus sample's infection concentration