495 citations · 499 across the 3 of their papers we have counts for
5 papers
On randomized sketching algorithms and the Tracy-Widom law
Daniel Ahfock, William J. Astle, Sylvia Richardson
There is an increasing body of work exploring the integration of random projection into algorithms for numerical linear algebra. The primary motivation is to reduce the overall com…
Statistical properties of sketching algorithms
Daniel Ahfock, William J. Astle, Sylvia Richardson
Sketching is a probabilistic data compression technique that has been largely developed in the computer science community. Numerical operations on big datasets can be intolerably s…
BATMAN-an R package for the automated quantification of metabolites from NMR spectra using a Bayesian Model
Jie Hao, William Astle, Maria De Iorio +1
Motivation: NMR spectra are widely used in metabolomics to obtain metabolite profiles in complex biological mixtures. Common methods used to assign and estimate concentrations of m…
A Bayesian Model of NMR Spectra for the Deconvolution and Quantification of Metabolites in Complex Biological Mixtures
William Astle, Maria De Iorio, Sylvia Richardson +2
Nuclear Magnetic Resonance (NMR) spectra are widely used in metabolomics to obtain profiles of metabolites dissolved in biofluids such as cell supernatants. Methods for estimating…
Population Structure and Cryptic Relatedness in Genetic Association Studies
William Astle, David J. Balding
We review the problem of confounding in genetic association studies, which arises principally because of population structure and cryptic relatedness. Many treatments of the proble…