2 papers
q-bio.GN2022
Therapeutic algebra of immunomodulatory drug responses at single-cell resolution
Jialong Jiang, Sisi Chen, Tiffany Tsou +10
Therapeutic modulation of immune states is central to the treatment of human disease. However, how drugs and drug combinations impact the diverse cell types in the human immune sys…
q-bio.GN2021
Active feature selection discovers minimal gene sets for classifying cell types and disease states with single-cell mRNA-seq data
Xiaoqiao Chen, Sisi Chen, Matt Thomson
Sequencing costs currently prohibit the application of single-cell mRNA-seq to many biological and clinical analyses. Targeted single-cell mRNA-sequencing reduces sequencing costs…