activity
20102015
most citedDnaA and the timing of chromosome replication in Escherichia coli as a function of growth rate

29 citations · 61 across the 7 of their papers we have counts for

collaborators

7 papers

q-bio.GN2015★ 2 cited

Ecological patterns of genome size variation and the origin of species in salamanders

Bianca Sclavi, John Herrick

Salamanders (urodela) have among the largest vertebrate genomes, ranging in size from 10 to over 80 pg. The urodela are divided into ten extant families each with a characteristic…

q-bio.GN2013★ 1 cited

Lineage specific reductions in genome size in salamanders are associated with increased rates of mutation

John Herrick, Bianca Sclavi

Very low levels of genetic diversity have been reported in vertebrates with large genomes, notably salamanders and lungfish [1-3]. Interpreting differences in heterozygosity, which…

q-bio.GN2013★ 2 cited

Slow Evolution of rag1 and pomc Genes in Vertebrates with Large Genomes

Bianca Sclavi, John Herrick

Growing evidence suggests that many vertebrate lineages are evolving at significantly different rates. As a first approximation of evolutionary rates, we assessed the amount of neu…

q-bio.GN2012

Gene silencing and large-scale domain structure of the E. coli genome

Mina Zarei, Bianca Sclavi, Marco Cosentino Lagomarsino

The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression. Motivated by the link…

q-bio.GN2012★ 29 cited

DnaA and the timing of chromosome replication in Escherichia coli as a function of growth rate

Matthew A. A. Grant, Chiara Saggioro, Ulisse Ferrari +3

Background: In Escherichia coli, overlapping rounds of DNA replication allow the bacteria to double in faster times than the time required to copy the genome. The precise timing of…

q-bio.GN2011

Slow evolution of vertebrates with large genomes

Bianca Sclavi, John Herrick

Darwin introduced the concept of the "living fossil" to describe species belonging to lineages that have experienced little evolutionary change, and suggested that species in more…

q-bio.GN2010★ 27 cited

Gene clusters reflecting macrodomain structure respond to nucleoid perturbations

Vittore F. Scolari, Bruno Bassetti, Bianca Sclavi +1

Focusing on the DNA-bridging nucleoid proteins Fis and H-NS, and integrating several independent experimental and bioinformatic data sources, we investigate the links between chrom…