49 citations · 57 across the 6 of their papers we have counts for
7 papers
Universality classes of interaction structures for NK fitness landscapes
Sungmin Hwang, Benjamin Schmiegelt, Luca Ferretti +1
Kauffman's NK-model is a paradigmatic example of a class of stochastic models of genotypic fitness landscapes that aim to capture generic features of epistatic interactions in mult…
The expected neutral frequency spectrum of linked sites
Luca Ferretti, Alexander Klassmann, Emanuele Raineri +3
We present an exact, closed expression for the expected neutral Site Frequency Spectrum for two neutral sites, 2-SFS, without recombination. This spectrum is the immediate extensio…
Decomposing the site frequency spectrum: the impact of tree topology on neutrality tests
Luca Ferretti, Alice Ledda, Guillaume Achaz +2
We investigate the dependence of the site frequency spectrum (SFS) on the topological structure of genealogical trees. We show that basic population genetic statistics - for instan…
Epistasis and constraints in fitness landscapes
Luca Ferretti, Daniel Weinreich, Benjamin Schmiegelt +4
Genotypic fitness landscapes are constructed by assessing the fitness of all possible combinations of a given number of mutations. In the last years, several experimental fitness l…
A simple model for the distribution of plasmid lengths
Alice Ledda, Luca Ferretti
Plasmids are major players in Horizontal Gene Transfer mechanisms, hence they are highly variable in their gene content and length. We propose a model for the fitness of a plasmid…
Watterson estimators for Next Generation Sequencing: from trios to autopolyploids
Luca Ferretti, Sebástian E. Ramos-Onsins
Several variations of the Watterson estimator of variability for Next Generation Sequencing (NGS) data have been proposed in the literature. We present a unified framework for gene…
Properties of neutrality tests based on allele frequency spectrum
Luca Ferretti, Giacomo Marmorini, Sebastian Ramos-Onsins
One of the main necessities for population geneticists is the availability of statistical tools that enable to accept or reject the neutral Wright-Fisher model with high power. A n…