2 papers
physics.med-ph2026
An Uncertainty-Guided Digital Twin Framework for Online Adaptive Proton Therapy in Head and Neck Cancer: A Feasibility Study
Yizhou Wu, Ryan J. Sanford, Huiqiao Xie +12
Objective: Head and neck (HN) proton therapy spans six to seven weeks of anatomical change, while offline replanning takes about a week. We present an uncertainty-guided digital tw…
physics.med-ph2026
A digital-twin framework for forecasting treatment-day imaging with contour uncertainty in adaptive proton radiotherapy
Yizhou Wu, Jie Ding, Justin Roper +6
Head-and-neck anatomy changes over a six-to-seven-week proton course, and the anatomy of a later week cannot be imaged when the plan is made. We present a digital-twin framework th…