69 citations · 95 across the 3 of their papers we have counts for
3 papers
Pattern Formation in a Coupled Membrane-Bulk Reaction-Diffusion Model for Intracellular Polarization and Oscillations
Frédéric Paquin-Lefebvre, Bin Xu, Kelsey L. DiPietro +2
Reaction-diffusion systems have been widely used to study spatio-temporal phenomena in cell biology, such as cell polarization. Coupled bulk-surface models naturally include compar…
Effect of Dedifferentiation on Time to Mutation Acquisition in Stem Cell-Driven Cancers
Alexandra Jilkine, Ryan N. Gutenkunst
Accumulating evidence suggests that many tumors have a hierarchical organization, with the bulk of the tumor composed of relatively differentiated short-lived progenitor cells that…
Asymptotic and bifurcation analysis of wave-pinning in a reaction-diffusion model for cell polarization
Yoichiro Mori, Alexandra Jilkine, Leah Edelstein-Keshet
We describe and analyze a bistable reaction-diffusion (RD) model for two interconverting chemical species that exhibits a phenomenon of wave-pinning: a wave of activation of one of…